Neueste Forschungsergebnisse unter Beteiligung des KKNMS

Auf dieser Seite stellen wir Ihnen unsere wissenschaftlichen Publikationen vor.

Erstveröffentlichungen:

Publikationen 2019

Longitudinal spinal cord atrophy in multiple sclerosis using the generalized boundary shift integral
Von Mocchia et al, erschienen in „Ann Neurol“ (Vol. 86, Nr. 5, November 2019)

Imaging the execution phase of neuroinflammatory disease models
Von Schumacher et al, erschienen in „Experimental Neurology“ (Vol. 320, Oktober 2019)

Clinical relevant cranio-caudal patterns of cervical cord atrophy evolution in MS
Von Rocca et al, erschienen in „Neurology“ (Oktober 2019)

Automated segmentation of changes in FLAIR-hyperintense white matter lesions in multiple sclerosis on serial magnetic resonance imaging
Von Schmidt et al, erschienen in „NeuroImage: Clinical“ (Vol. 23, 2019)

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity
Von Fecher et al, erschienen in „Nat. Neurosci“ (September 2019)

Intrathecal B-cell accumulation and axonal damage distinguish MRI-based benign from aggressive onset in MS
Von Engel et al, erschienen in „Neurol Neuroimmunol Neuroinflamm“ (Vol. 6, Nr. 5, September 2019)

Pretreatment anti-thyroid autoantibodies predict thyroid autoimmunity secondary to alemtuzumab
Von Ruck et al, erschienen in „EBioMedicine“ (Vol. 46, August 2019)

CD20 monoclonal antibodies for the treatment of multiple sclerosis: up-to-date
Von Ancau et al, erschienen in „Expert Opin Biol Ther“ (Vol. 19, Nr. 8, August 2019)

A large case-control study on vaccination as risk factor of multiple sclerosis
Von Hapfelmeier et al, erschienen in „Neurology“ (Vol. 93, Nr. 9, August 2019)

Dendritic Cell Accumulation in the Gut and Central Nervous System Is Differentially Dependent on α4 Integrins
Von Sie et al, erschienen in „J Immunol“ (Vol. 203, Nr. 6, September 2019)

Validation of mean upper cervical cord area (MUCCA) measurement techniques in multiple sclerosis (MS): High reproducibility and robustness to lesions, but large software and scanner effects
Von Weeda et al, erschienen in „Neuroimage Clin“ (Vol. 24, August 2019)

Optical coherence tomography in myelin-oligodendrocyte-glycoprotein antibody-seropositive patients: a longitudinal study
Von Oertel et al, erschienen in „J Neuroinflammation“ (Vol. 16, Nr. 1, Juli 2019)

Single-subject structural cortical networks in clinically isolated syndrome
Von Collorone et al, erschienen in „Mult Scler“ (Juli 2019)

Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany
Von Bittner et al, erschienen in „Nervenarzt“ (Juli 2019)

Cerebrospinal fluid parameters associated with early MRI activity in patients with multiple sclerosis
Von Klein et al, erschienen in „

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis
Von International Multiple Sclerosis Genetics Consortium, erschienen in „Nat Commun“ (Vol. 10, Nr. 1, Mai 2019)

Association of Intrathecal Immunoglobulin G Synthesis With Disability Worsening in Multiple Sclerosis
Von Gasperi et al, erschienen in „JAMA Neurol“ (Vol. 76, Nr. 7, Juli 2019)

MCC950 blocks enhanced interleukin-1β production in patients with NLRP3 low penetrance variants
Von Schuh et al, erschienen in „Clin Immunol“ (Vol. 203, Juni 2019)

The Glycosylation Site of Myelin Oligodendrocyte Glycoprotein Affects Autoantibody Recognition in a Large Proportion of Patients
Von Marti Fernandez et al, erschienen in „Front Immunol“ (Vol. 10, Juni 2019)

Alemtuzumab in Multiple Sclerosis: Short- and Long-Term Effects of Immunodepletion on the Peripheral Treg Compartment
Von Haas et al, erschienen in „Front Immunol“ (Vol. 19, Juni 2019)

Immunophenotyping of cerebrospinal fluid cells in ischemic stroke
Von Schulte-Mecklenbeck et al, erschienen in „Eur J Neurol“ (Vol. 26, Nr. 6, Juni 2019)

Drug-use patterns and severe adverse events with disease-modifying drugs in patients with multiple sclerosis: a cohort study based on German claims data
Von Simbrich et al, erschienen in „Neuropsychiatr Dis Treat“ (Vol. 15, Mai 2019)

Optimal intereye difference thresholds by optical coherence tomography in multiple sclerosis: An international study
Von Nolan-Kenney et al, erschienen in „Ann Neurol“ (Vol. 85, Nr. 5, Mai 2019)

VLA-2 blockade in vivo by vatelizumab induces CD4+FoxP3+ regulatory T cells
Von Breuer et al, erschienen in „Int Immunol“ (Vol. 31, Nr. 6, Mai 2019)

Evidence for a white matter lesion size threshold to support the diagnosis of multiple sclerosis
Von Grahl et al, erschienen in „Mult Scler Relat Disord“ (Vol. 29, April 2019)

Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis
Von Graetz et al, erschienen in „Mult Scler“ (Vol. 25, Nr. 5, April 2019)

Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials
Von Buck et al, erschienen in „Mult Scler“ (Vol. 25, Nr. 4, April 2019)

Risks and risk management in modern multiple sclerosis immunotherapeutic treatment
Von Klotz et al, erschienen in „Ther Adv Neurol Disord“ (Vol. 12, April 2019)

Increased cerebrospinal fluid albumin and immunoglobulin A fractions forecast cortical atrophy and longitudinal functional deterioration in relapsing-remitting multiple sclerosis
Von Kroth et al, erschienen in „Mult Scler“ (Vol. 25, Nr. 3, März 2019)

β-Synuclein reactive T cells induce autoimmune CNS grey matter degeneration
Von Lodygin et al, erschienen in „Nature“ (Vol.566, Februar 2019)

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
Von Masuda et al, erschienen in „Nature“ (Vol. 566, Nr. 7744, Februar 2019)

Calcium influx trough plasma-membrane nanopores drives axon degeneration in an animal model of multiple sclerosis
Von Witte et al, erschienen in „Neuron“ (Vol. 101, Nr. 4, Februar 2019)

Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS)
Von Johnen et al, erschienen in „J Neurol“ (Vol. 266, Nr. 2, Februar 2019)

Blimp1 prevents methylation of Foxp3 and loss of regulatory T cell identity at sites of inflammation
Von Garg et al, erschienen in „Cell Rep“ (Vol. 26, Nr. 7, Februar 2019)

Optical coherence tomography angiography indicates associations of the retinal vascular network and disease activity in multiple sclerosis
Von Feucht et al, erschienen in „Mult Scler“ (Vol. 25, Nr. 2, Februar 2019)

Stars are not in outer space: Astrocytes respond to environmental cues
Von Korn, erschienen in „Cell“ (Vol. 176, Nr. 3, Januar 2019)

Efficacy and safety of alemtuzumab versus fingolimod in RRMS after natalizumab cessation
Von Pfeuffer et al, erschienen in „J Neurol“ (Vol. 266, Nr.1, Januar 2019)

Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation
Von Jordão et al, erschienen in „Science“ (Vol. 363, Januar 2019)

Publikationen 2018

Myeloid-derived suppressor cells control B cells within the central nervous system during autoimmunity
Von Knier et al, erschienen in „Nat Immunol“ (Vol. 19, Nr. 12, Dezember 2018)

Vitiligo after alemtuzumab treatment: autoimmunity is not all about B cells
Von Ruck et al, erschienen in „Neurology“ (Vol. 91, Nr. 24, Dezember 2018)

Retinal ganglion cell loss in neuromyelitis optica: a longitudinal study
Von Oertel et al, erschienen in „J Neurol Neurosurg Psychiatry“ (Vol. 89, Nr. 12, Dezember 2018)

Neurofascin-155 IgM autoantibodies in patients with inflammatory neuropathies
Von Doppler K et al, erschienen in „J Neurol Neurosurg Psychiatry“ (Vol. 89, Nr. 11, November 2018)

Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk
Von International Multiple Sclerosis Genetics Consortium, erschienen in „Cell“ (Vol. 175, Nr. 6, November 2018)

Discriminative power of intra-retinal layers in early multiple sclerosis using 3D OCT imaging
Von Seitz CB et al, erschienen in „J Neurol“ (Vol. 265, Nr. 10, Oktober 2018)

Apheresis therapies for NMOSD attacks: a retrospective study of 207 therapeutic interventions
Von Kleiter I et al, erschienen in „Neurol Neuroimmunol Neuroinflamm.“ (Vol. 5, Nr. 6, September 2018)

Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration
Von Tay et al, erschienen in „Acta Neuropathol Commun“ (Vol. 6, Nr. 1, September 2018)

Shedding of BAFF/APRIL Receptors Controls B Cells
Von Meinl E et al, erschienen in „Trends Immunol.“ (Vol. 39, Nr. 9, September 2018)

Neuroimmunologische Register in Deutschland
Von Thiel S et al, erschienen in „Akt Neurol“ (Vol. 45, Nr. 01, 2018)

Monuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model
Von Locatelli et al, erschienen in „N Neuroscience“ (Nr. 21, August 2018)

Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein
Von Spadaro M et al, erschienen in „Ann Neurol.“ (Vol. 84, Nr. 2, August 2018)

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus
Von Breuer et al, erschienen in „N Neuroinflamm“ (August 2018)

Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid – Results from the ToFingo Successor Study
Von Lohmann L et al, erschienen in „Frontiers in Immunology“ (Vol. 9, Juli 2018)

Fatigue in multiple sclerosis: Associations with clinical, MRI and CSF parameters
Von Pongratz (geb. Biberacher) V et al, erschienen in  „Multiple Sclerosis“ (Vol. 24, Nr. 8, Juli 2018)

DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis
Von Kular L et al, erschienen in „Nat Commun“ (Vol. 9, Nr. 1, Juni 2018)

Interleukin-6: Designing specific therapeutics for a complex cytokine
Von Garbers et al, erscheinen in „Nat Rev Drug Discov“ (Vol. 17, Nr. 6, Juni 2018)

Immunophenotyping of cerebrospinal fluid cells by Chipcytometry
Von Hümmert MW et al, erschienen in „Journal of Neuroinflammation“ (Vol. 15, Nr. 1, Mai 2018)

Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3
Von Schmidt A et al, erschienen in „BMC Biol“ (Vol. 16, Nr. 1, Mai 2018)

MOG encephalomyelitis: international recommendations on diagnosis and antibody testing
Von Jarius S et al, erschienen in „Journal of Neuroinflammation“ (Vol. 15, Nr. 1, Mai 2018)

Treatment choices and neuropsychological symptoms of a large cohort of early MS
Von Bismarck O et al, erschienen in „Neurol Neuroimmunol Neuroinflamm.“ (Vol. 5, Nr. 3, Mai 2018)

Autoantibodies Against the Node of Ranvier in Seropositive Chronic Inflammatory Demyelinating Polyneuropathy: Diagnostic, Pathogenic, and Therapeutic
Von Vural A et al, erschienen in „Front Immunol.“ (Vol. 9, Mai 2018)

Intrathecal immunoglobulin M production: A promising high-risk marker in clinically isolated syndrome patients
Von Huss A et al, erschienen in „Ann Neurol.“ (Vol. 83, Nr. 5, Mai 2018)

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation
Von Voet et al, erschienen in „Nat Commun“ (Vol. 9, Nr. 1, Mai 2018)

Treatment response to dimethyl fumarate is characterized by disproportionate CD8+ T cell reduction in MS
Von Fleischer V et al, erschienen in „Mult Scler“ (Vol. 24, Nr. 5, April 2018)

Differences in the Reponses to Apheresis Therapy of Patients With 3 Histopathologically Classified Immunopathological Patterns of Multiple Sclerosis
Von Stork L et al, erschienen in „JAMA Neurology“ (Vol. 75, Nr. 4, April 2018)

Anti-JCV serology during natalizumab treatment: Review and meta-analysis of 17 independent patient cohorts analyzing anti-John Cunningham polyoma virus sero-conversion rates under natalizumab treatment and differences between technical and biological sero-converters
Von Schwab N et al, erschienen in „Multiple Sclerosis“ (Vol. 24, Nr. 5, April 2018)

Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials
Von Buck et al, erschienen in „Multiple Sclerosis Journal“ (doi:10.1177/1352458518763089, März 2018)

Preservation of neuronal function as measured by clinical and MRI endpoints in relapsing-remitting multiple sclerosis: how effective are current treatment strategies?
Von Graetz C et al, erschienen in „Expert Rev Neurother.“ (Vol. 18, Nr. 3, März 2018)

MOG-IgG in primary and secondary chronic progressive multiple sclerosis: a multicenter study of 200 patients and review of the literature
Von Jarius S et al, erschienen in „Journal of Neuroinflammation“ (Vol. 15, Nr. 1, März 2018)

Interferon-beta specific T cells are associated with the development of neutralizing antibodies in interferon-beta treated multiple sclerosis patients
Von Kalluri SR et al,erschienen in „J Autoimmun.“ (Vol. 88, März 2018)

Nurse-led immunotreatment DEcision Coaching In people with Multiple Sclerosis (DECIMS) – Feasibility testing, pilot randomised controlled trial and mixed methods process evaluation
Von Rahn A et al, erschienen in „International Journal of Nursing Studies“ (Vol. 78, Februar 2018)

Sex bias in MHC I-associated shaping of the adaptive immune system
Von Schneider-Hohendorf T et al, erschienen in „Proc Natl Acad Sci U S A.“ (Vol. 115, Nr. 9, Februar 2018)

Defining response profiles after alemtuzumab: Rare paradoxical disease exacerbation
Von Wiendl H et al, erschienen in „Neurology“ (Vol. 90, Nr. 7, Februar 2018)

Neuroimmunological Registries in Germany
Von Thiel S et al, erschienen in „Neurology International Open 2018“ (Vol. 2, Nr. 1, Februar 2018)

Alemtuzumab Improves Cognitive Processing Speed in Active Multiple Sclerosis-A Longitudinal Observational Study
Von Riepl E et al, erschienen in „Front Neurol“ (Vol. 8; Januar 2018; eCollection 2017)

IL-23 (Interleukin-23)-Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke
Von Gelderblom et al, erschienen in „Stroke“ (Vol. 49, Nr. 1, Januar 2018)

Baló’s concentric sclerosis is immunologically distinct from multiple sclerosis: results from retrospective analysis of almost 150 lumbar punctures
Von Jarius S et al, erschienen in „Journal of Neuroinflammation“ (Vol. 15, Nr. 1, Januar 2018)

Publikationen 2017

Incidence of multiple sclerosis in Germany: A cohort study applying different case Definitions based on claims data
Von Schmedt et al, erschienen in „Neuroepidemiology“ (Vol. 49, Nr. 3-4, Dezember 2017)

Dual action by fumaric acid esters synergistically reduces adhesion to human endothelium
Von Breuer et al, erschienen in „Mult Scler“ (2017 Oct 1:1352458517735189.)

Cladribine – an old newcomer for pulsed immune reconstitution in MS
Von Wiendl, erschienen in „Nat Rev Neurol.“ (Vol. 13; Nr. 10; Oktober 2017)

Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice
Von Berer et al, erschienen in „Proc Natl Acad Sci U S A.“ (Vol. 114, Nr. 40, Oktober 2017)

A gut feeling about multiple sclerosis
Von Quintana und Prinz, erschienen in „Proc Natl Acad Sci U S A.“ (Vol. 114, Nr. 40, Oktober 2017)

Cortical pathology in multiple sclerosis detected by the T1/T2-weighted ratio from routine magnetic resonance imaging
Von Righart R et al, erschienen in „Annals of Neurology“ (Vol. 82, Nr. 4, Oktober 2017)

A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease
Von Mass et al, erschienen in „Nature“ (Vol. 549, Nr. 7672, September 2017)

A novel imaging technique for better detecting new lesions in multiple sclerosis
Von Eichinger P et al, erschienen in „Journal of Neurology“ (Vol. 264, Nr. 9, September 2017)

Can immune reprogramming with alemtuzumab induce permanent remission in multiple sclerosis?
Von Wiendl et al, erschienen in „Neurology“ (Vol. 89, Nr. 11, September 2017)

Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
Von Deczkowska et al, erschienen in „Nat Commun“ (Vol. 8, Nr. 1, September 2017)

Type I interferon pathway in CNS homeostasis and neurological disorders
Von Blank und Prinz, erschienen in „Glia“ (Vol. 65, Nr. 9, September 2017)

Microglia in steady state
Von Kierdorf und Prinz, erschienen in „J Clin Invest“ (Vol. 127, Nr. 9, September 2017)

Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood
Von Hagemeyer et al, erschienen in „Acta Neuropathol“ (Vol. 134, Nr. 3, September 2017)

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response
Von Stellmann JP et al, erschienen in „Journal of Neurology, Neurosurgery and Psychiatry“ (Vol. 88, Nr. 8, August 2017)

Pattern II and pattern III MS are entities distinct from pattern I MS: evidence from cerebrospinal fluid analysis
Von Jarius S et al, erschienen in „Journal of Neuroinflammation“ (Vol. 14, Nr. 1, August 2017)

A new graphical format to communicate treatment effects to patients- a web-based randomized-controlled trial
Von Kasper et al, erschienen in „Health Expectations“ (Vol. 20, Nr. 4, August 2017)

Relevance of early cervical cord volume loss in the disease evolution of clinically isolated syndrome and early multiple sclerosis: a 2-year follow-up study
Von Hagström IT et al, erschienen in „Journal of Neurology“ (Vol. 264, Nr. 7, Juli 2017)

Volume versus surface-based cortical thickness measurements: A comparative study with healthy controls and multiple sclerosis patients
Von Rhigart et al, erschienen in „PLOS ONE“ (Vol. 12, Nr. 7, Juli 2017)

Gut-CNS-Axis as Possibility to Modulate Inflammatory Disease Activity-Implications for Multiple Sclerosis
Von Fleck at al, erschienen in „Int J Mol Sci“ (Vol. 18, Nr. 7, Juli 2017)

Influence of female sex and fertile age on neuromyelitis optica spectrum disorders
Von Borisow N et al, erschienen in „Multiple Sclerosis“ (Vol. 23, Nr. 8, Juli 2017)

Association of Retinal Architecture, Intrathecal Immunity, and Clinical Course in Multiple Sclerosis: A cohort study
Von Knier B et al, erschienen in „JAMA Neurology“ (Vol. 74, Nr. 7, Juli 2017)

Daclizumab for the treatment of relapsing-remitting multiple sclerosis
Von Herwerth und Hemmer, erschienen in „Expert Opin Biol Ther“ (Vol. 17, Nr. 6, Juni 2017)

Laquinimod enhances central nervous system barrier functions
Von Lühder et al, erschienen in „Neurobiol Dis“ (Vol. 102, Juni 2017)

A new fate mapping system reveals context-dependent random or clonal expansion of microglia
Von Tay et al, erschienen in „Nature Neuroscience“ (Vol. 20, Nr. 6, Juni 2017)

Distinct pattern of lesion distribution in multiple sclerosis is associated with different circulating T-helper and helper-like innate lymphoid cell subsets
Von Gross et al, erschienen in „Mult Scler“ (Vol. 23, Nr. 7, Juni 2017)

Multifrequency magnetic resonance elastography of the brain reveals tissue degeneration in neuromyelitis optica spectrum disorder
Von Streitberger et al, erschienen in „Eur Radiol“ (Vol. 27, Nr. 5, Mai 2017)

Central Atrophy Early in Multiple Sclerosis: Third Ventricle Volumetry versus Planimetry
Von Lutz et al, erschienen in „J Neuroimaging“ (Vol. 27, Nr. 3, Mai 2017)

Human Plasmacytoid Dendritic Cells Display and Shed B Cell Maturation Antigen upon TLR Engagement
Von Schuh et al, erschienen in „J Immunol“ (Vol. 198, Nr. 8, April 2017)

Natalizumab-associated PML: Challenges with incidence, resulting risk, and risk stratification
Schwab N et al, erschienen in „Neurology“ (Vol. 88, Nr. 12, März 2017)

Increased structural white and grey matter network connectivity compensates for functional decline in early multiple sclerosis
Von Fleischer V et al, erschienen in „Multiple Sclerosis“ (Vol. 23, Nr. 3, März 2017)

Ontogeny and homeostasis of CNS myeloid cells
Von Prinz et al, erschienen in „Nature Immunology“ (Vol. 18, Nr. 4, März 2017)

Deletional tolerance prevents AQP4 directed autoimmunity in mice
Von Vogel AL et al, erschienen in „European Journal of Immunology“ (Vol. 47, Nr. 3, März 2017)

Reply to Liu et al.: Haplotype matters: CD226 polymorphism as a potential trigger for impaired immune regulation in multiple sclerosis
Von Gross CC et al, erschienen in „Proceedings of the National Academy of Science of the USA“ (Vol. 114, Nr. 6, Februar 2017)

The role of peripheral immune cells in the CNS in steady state and disease
Von Prinz und Priller, erschienen in „Nature Neuroscience“ (Vol. 20, Nr. 2, Februar 2017)

Multiple sclerosis in 2016: Immune-directed therapies in MS – efficacy and limitations
Von Hemmer B et al, erschienen in „Nature Reviews. Neurology“ (Vol. 13, Nr. 2, Februar 2017)

Th17 cells: A prognostic marker for MS rebound after natalizumab cessation?
Von Haas et al, erschienen in „Mult Scler“ (Vol. 23, Nr. 1, Januar 2017)

B-cell populations discriminate between pediatric- and adult-onset multiple sclerosis
Von Schwarz et al, erschienen in „Neurol Neuroimmunol Neuroinflamm“ (Vol. 4, Nr. 1: e309, Januar 2017)

Publikationen 2016

Regulatory Functions of Natural Killer Cells in Multiple Sclerosis
Von Gross et al, erschienen in „Front Immunol“ (Vol. 7, Dezember 2016, eCollection 2016)

Myeloid Dendritic Cells exhibit Defects in Activation and Function in Patients with Multiple Sclerosis
Von Haas, erschienen in „J Neuroimmunol“ (Vol. 301, Dezember 2016)

Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria: A German-Austrian retrospective multicenter study in patients with a clinically isolated syndrome
Von Huss et al, erschienen in „J Neurol“ (Vol. 263, Nr. 12, Dezember 2016)

Validation of a multiplexing technique to determine the intrathecal, polyspecific antiviral immune response in multiple sclerosis
Von Huss et al, erschienen in „Expert Review of Molecular Diagnostics“ (Vol. 16, Nr. 12, Dezember 2016)

Brain parenchymal damage in neuromyelitis optica spectrum disorder – A multimodal MRI study
Von Pache et al, erschienen in „European Radiology“ (Vol. 26, Nr. 12, Dezember 2016)

Patientenwiderrufe als Herausforderung für das Datenmanagement – ein Lösungsvorschlag für die Forschungspraxis
Von Antony et al, erschienen in „e-Health 2016“

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients
Von Pache et al, erschienen in „J Neuroinflammation“ (Vol. 13, 1, November 2016)

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement – frequency, presentation and outcome
Von Jarius et al, erschienen in „J Neuroinflammation“ (Vol. 13, 1, November 2016)

Intra- and interscanner variability of magnetic resonance imaging based volumetry in multiple sclerosis
Von Biberacher et al, erschienen in „Neuroimage“ (Vol. 142, November 2016)

Metabolic Patterns in Chronic Multiple Sclerosis Lesions and Normal-appearing White Matter: Intraindividual Comparison by Using 2D MR Spectroscopic Imaging
Von Fleischer et al, erschienen in „Radiology“ (Vol. 281, Nr. 2, November 2016)

Screening for MOG-IgG and 27 other anti-glial and anti-neuronal autoantibodies in ‚pattern II multiple sclerosis‘ and brain biopsy findings in a MOG-IgG-positive case
Von Jarius et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 22, Nr. 12, Oktober 2016)

Short-term MRI measurements as predictors of EDSS progression in relapsing-remitting multiple sclerosis: Grey matter atrophy but not lesions are predictive in a real-life setting
Von von Gumbertz et al, erschienen in „PeerJ“ (Vol. 4: e2442.eCollection, September 2016)

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome
Von Jarius et al, erschienen in „J Neuroinflammation“ (Vol. 13, Nr. 1, September 2016)

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin
Von Jarius et al, erschienen in „J Neuroinflammation“ (Vol. 13, Nr. 1, September 2016)

Comprehension of confidence intervals – development and piloting of patient information materials for people with multiple sclerosis: qualitative study and pilot randomised controlled trial
Von Rahn et al, erschienen in „BMC Med Inform Decis Mak“ (Vol. 16, Nr. 1, September 2016)

Vascular, glial, and lymphatic immune gateways of the central nervous system
Von Engelhardt et al, erschienen in „Acta Neuropathol“ (Vol. 132, Nr. 3, September 2016)

Calibrating random forests for probability estimation
Von Dankowski und Ziegler, erschienen in „Stat Med“ (Vol. 35, Nr. 22, September 2016)

CD4+HLA-G+ regulatory T cells: Molecular signature and pathophysiological relevance
Von Pankratz et al, erschienen in „Hum Immunol“ (Vol. 77, Nr. 9, September 2016)

Fine specificity of the antibody response to Epstein-Barr nuclear antigen-2 and other Epstein-Barr virus proteins in patients with clinically isolated syndrome: A peptide microarray-based case-control study
Von Schlemm et al, erschienen in „J Neuroimmunol“ (Vol. 297, August 2016)

The force awakens: insights into the origin and formation of microglia
Von Tay et al, erschienen in „Curr Opin Neurobiol“ (Vol. 39, August 2016)

Change in autoantibody and cytokine responses during the evolution of neuromyelitis optica in patients with systemic lupus erythematosus: A preliminary study
Von Kovacs et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 22, Nr. 9, August 2016)

Transcriptome-based profiling of yolk sac-derived macrophage development and identification of a role of Irf8 in their maturation
Von Hagemeyer et al, erschienen in „EMBO J.“ (Vol. 35, Nr. 16, August 2016)

Tissue damage within normal appearing white matter in early multiple sclerosis: assessment by the ratio of T1- and T2-weighted MR image intensity
Von Beer et al, erschienen in „Journal of Neurology“ (Vol. 263, Nr. 8, August 2016)

Features of Human CD3+CD20+ T Cells
Von Schuh et al, erschienen in „J Immunol.“ (Vol. 197, Nr. 4, August 2016)

PML risk stratification using anti-JCV antibody index and L-selectin
Von Schwab et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 22, Nr. 8, Juli 2016)

Iron and Non-Iron-Related Characteristics of Multiple Sclerosis and Neuromyelitis Optica Lesions at 7T MRI
Von Chawla et al, erschienen in „AJNR Am J Neuroradiol.“ (Vol. 37, Nr. 7, Juli 2016)

MRI phase changes in multiple sclerosis vs neuromyelitis optica lesions at 7T
Von Sinnecker et al, erschienen in „Neurol Neuroimmunol Neuroinflamm.“ (Vol. 3, Nr. 4, Juli 2016)

Origin, fate and dynamics of macrophages at central nervous system interfaces
Von Goldmann et al, erschienen in „Nat Immunol.“ (Vol. 17, Nr. 7, Juli 2016)

Monitoring von Blutparametern unter verlaufsmodifizierender MS-Therapie- Substanzspezifische Relevanz und aktuelle Handlungsempfehlungen
Von Klotz et al, erschienen in „Nervenarzt“ (Vol. 87, Nr. 6, Juni 2016)

Neuromyelitis optica does not impact periventricular venous density versus healthy controls: a 7.0 Tesla MRI clinical study
Von Schumacher et al, erschienen in „MAGMA“ (Vol. 29, Nr. 3, Juni 2016)

Aquaporin-4 IgG autoimmune syndrome and immunoreactivity associated with thyroid cancer
Von Soelberg et al, erschienen in „Neurol Neuroimmunol Neuroinflamm.“ (Vol. 3, Nr. 4, Juni 2016)

Autoantibodies to MOG in a distinct subgroup of adult multiple sclerosis
Von Spadaro et al, erschienen in „Neurol Neuroimmunol Neuroinflamm.“ (Vol. 3, Nr. 5, Juni 2016)

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation
Von Andlauer et al, erschienen in „Science Advances“ (Vol. 2, Nr. 6, Juni 2016)

Antibody producing B lineage cells invade the central nervous system predominantly at the time of and triggered by acute Epstein-Barr virus infection: A hypothesis on the origin of intrathecal immunoglobulin synthesis in multiple sclerosis
Von Otto et al, erschienen in „Med Hypotheses“ (Vol. 91, Juni 2016)

Ablagerung von gadoliniumhaltigen Kontrastmitteln im Gehirn nach mehrfacher Anwendung: Konsequenzen für den Einsatz der MRT bei Diagnosestellung und Verlaufsbeurteilung der Multiplen Sklerose?
Von Lukas et al, erschienen in „Akt Neurol“ (Vol. 43, Nr. 4, Mai 2016)

Hypovitaminosis D upscales B-cell immunoreactivity in multiple sclerosis
Von Haas et al, erschienen in „J Neuroimmunol.“ (Vol. 294, Mai 2016)

Detection of intrathecal immunoglobulin G synthesis by capillary isoelectric focusing immunoassay in oligoclonal band negative multiple sclerosis
Von Halbgebauer et al, erschienen in „J Neurol.“ (Vol. 263, Nr. 5, Mai 2016)

In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology
Von Herwerth et al, erschienen in „Ann Neurol.“ (Vol. 79, Nr. 5, Mai 2016)

Early silent microstructural degeneration and atrophy of the thalamocortical network in multiple sclerosis
Von Deppe et al, erschienen in „Hum Brain Mapp.“ (Vol. 37, Nr. 5, Mai 2016)

Secondary Progression in Multiple Sclerosis: Neuronal Exhaustion or Distinct Pathology?
Von Larochelle et al, erschienen in „Trends Neurosci“ (Vol. 39, Nr. 5, Mai 2016)

Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation
Von Gross et al, erschienen in „Proc Natl Acad Sci U S A.“ (Vol. 113, Nr. 21, Mai 2016)

Multicenter Validation of Mean Upper Cervical Cord Area Measurements from Head 3D T1-Weighted MR Imaging in Patients with Multiple Sclerosis
Von Liu et al, erschienen in „Am J Neuroradiol.“ (Vol. 37, Nr. 4, April 2016)

Brain endothelial and epithelial IFNAR is key for virus-induced sickness behavior and cognitive impairment
Von Blank et al, erschienen in „Immunity“ (Vol. 44, Nr. 4, April 2016)

Normal volumes and microstructural integrity of deep gray matter structures in AQP4+ NMOSD
Von Finke et al, erschienen in „Neurol Neuroimmunol Neuroinflamm.“ (Vol. 3, Nr. 3, April 2016)

Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI
Von Blaabjerg et al, erschienen in „Neurol Neuroimmunol Neuroinflamm.“ (Vol. 3, Nr. 3, April 2016)

Efficacy of glatiramer acetate in neuromyelitis optica spectrum disorder: a multicenter retrospective study
Von Ayzenberg et al, erschienen in „J Neurol.“ (Vol. 263, Nr. 3, März 2016)

In vivo and in vitro effects of multiple sclerosis immunomodulatory therapeutics on glutamatergic excitotoxicity
Von Luchtman et al, erschienen in „J Neurochem“ (Vol. 136, Nr. 5, März 2016)

The search for the target antigens of multiple sclerosis, part 2: CD8+ T cells, B cells, and antibodies in the focus of reverse-translational research
Von Hohlfeld et al, erschienen in „Lancet Neurol.“ (Vol. 15, Nr. 3, März 2016)

Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease
Von Flach et al, erschienen in „Proc Natl Acad Sci U S A.“ (Vol. 113, Nr. 12, März 2016)

Therapy with natalizumab is associated with high JCV seroconversion and rising JCV index values
Von Schwab et al, erschienen in „Neurol Neuroimmunol Neuroinflamm“ (Vol. 3, Februar 2016)

Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis
Von Metz et al, erschienen in „Neurol Neuroimmunol Neuroinflamm.“ (Vol. 3, Nr. 2, Februar 2016)

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid
Von Schläger et al, erschienen in „Nature“ (Vol. 530, Nr. 7590, Februar 2016)

Distinct functionality of neutrophils in multiple sclerosis and neuromyelitis optica
Von Hertwig et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 22, Nr. 2, Februar 2016)

Structural correlates for fatigue in early relapsing remitting multiple sclerosis
Von Wilting et al, erschienen in „European Radiology“ (Vol. 26, Nr. 2, Februar 2016)

Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses
Von Kleiter et al, erschienen in „Ann Neurol.“ (Vol. 79, Nr. 2, Februar 2016)

CNS myeloid cells as drug targets: current status and translational challenges
Von Biber et al, erschienen in „Nat Rev Drug Disc“ (Vol. 15, Nr. 2, Februar 2016)

Fine-tuning of type I IFN-signaling in microglia- implications for homeostasis, CNS autoimmunity and interferonopathies
Von Goldmann et al, erschienen in „Curr Opin Neurobiol“ (Vol. 36, Februar 2016)

Evidence for early, non-lesional cerebellar damage in patients with multiple sclerosis: DTI measures correlate with disability, atrophy, and disease duration
Von Deppe et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 22, Nr. 1, Januar 2016)

Low 25-hydroxyvitamin D, but not the bioavailable fraction of 25-hydroxyvitamin D, is a risk factor for multiple sclerosis
Von Behrens et al, erschienen in „Eur J Neurol.“ (Vol. 23, Nr. 1, Januar 2016)

Changing requirements and resulting needs for IT-infrastructure for longitudinal research in the neurosciences
Von Buckow et al, erschienen in „Neurosci Res.“ (Vol. 102, Januar 2016)

A MS-lesion pattern discrimination plot based on geostatistics
Von Marschallinger et al, erschienen in „Brain and Behavior“ (Vol. 6, Nr. 3, Januar 2016)

Analysis of Lymphocytic DNA Damage in Early Multiple Sclerosis by Automated Gamma-H2AX and 53BP1 Foci Detection: A Case Control Study
Von Rasche et al, erschienen in „PLoS One“ (Vol. 11, Nr.1, Januar 2016)

In vivo visualization of (auto)immune processes in the central nervous system of rodents
Von Schläger et al, erschienen in „Methods Mol Biol.“ (Vol. 1304, 2016)

Detection of Autoantibodies Against Myelin Oligodendrocyte Glycoprotein in Multiple Sclerosis and Related Diseases
Von Spadaro M und Meinl E, erschienen in „Methods „Mol Biol.“ (Vol. 1304, 2016)

Publikationen 2015

Investigation of sex-specific effects of apolipoprotein E on severity of EAE and MS
Von Schrewe et al, erschienen in „Journal of Neuroinflammation“ (Vol. 12, Nr. 1, Dezember 2015)

FTY720 (fingolimod) treatment tips the balance towards less immunogenic antigen-presenting cells in patients with multiple sclerosis
Von Luessi et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 21, Nr. 14, Dezember 2015)

Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array
Von Dankowski et al, erschienen in „Genet Epidemiol.“ (Vol. 39, Nr. 8, Dezember 2015)

Fingolimod does not impair T-cell release from the thymus and beneficially affects Treg function in patients with multiple sclerosis
Von Haas et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 21, Nr. 12, Oktober 2015)

Putaminal alteration in multiple sclerosis patients with spinal cord lesions
Von Zimmermann et al, erschienen in „Journal of Neural Transmission“ (Vol. 122, Nr. 10, Oktober 2015)

Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis
Von Keller et al, erschienen in „J Neuroinflammation“ (Vol. 12, Oktober 2015)

Class II HLA interactions modulate genetic risk for multiple sclerosis
Von Moutsianas et al, erschienen in „Nat Genet.“ (Vol. 47, Nr. 10, Oktober 2015)

Central Role of Th2 and Tc2 Lymphocytes in Multiple Sclerosis Pattern II Demyelinating Lesions
Von Planas et al, erschienen in „Annals of Clinical and Translational Neurology“ (Vol. 2, Nr. 9, September 2015)

Relevance of Magnet Resonance Tomography in the Diagnosis and Assessment of Course of Disease in Patients with Multiple Sclerosis
Von Lukas C und Sailer M, erschienen in „Fortschr Neurol Psychiatr.“ (Vol. 83, Nr. 9, September 2015)

Magnetresonanztomografie bei Patienten mit Multipler Sklerose: Relevanz in der Diagnose und Verlaufsbeurteilung
Von Lukas C und Sailer M, erschienen in „Klin Neurophysiol“ (Vol. 46, Nr. 3, September 2015)

Natalizumab exerts a suppressive effect on surrogates of B cell function in blood and CSF
Von Warnke et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 21, Nr. 8, Juli 2015)

Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study
Von Kuhle et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 21, Nr. 8, Juli 2015)

Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9
Von Lindner et al, erschienen in „Brain“ (Vol. 138, Pt 7, Juli 2015)

Identification of cortical lesions using DIR and FLAIR in early stages of multiple sclerosis
Von Kolber et al, erschienen in „Journal of Neurology“ (Vol. 262, Nr. 6, Juni 2015)

γ-secretase directly sheds the survival receptor BCMA from plasma cells
Von Laurent et al, erschienen in „Nature Communications“ (Vol. 6, Juni 2015)

Atrophy and structural variability of the upper cervical cord in early multiple sclerosis
Von Biberacher et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 21, Nr. 7, Juni 2015)

Listeria Meningitis Complicating Alemtuzumab Treatment in Multiple Sclerosis-Report of Two Cases
Von Rau et al, erschienen in „Int J Mol Sci.“ (Vol. 16, Nr. 7, Juni 2015)

Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography
Von Bennett et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 21, Nr. 6, Mai 2015)

B lymphocytes in neuromyelitis optica
Von Bennett et al, erschienen in „Neurol Neuroimmunol Neuroinflamm.“ (Vol. 2, Nr. 3, Mai 2015)

A human post-mortem brain model for the standardization of multi-centre MRI studies
Von Droby et al, erschienen in „Neuroimage“ (Vol. 110, April 2015)

Role of the innate and adaptive immune responses in the course of multiple sclerosis
Von Hemmer et al, erschienen in „Lancet Neurology“ (Vol. 14, Nr. 4, April 2015)

Glial Cells Express Nuclear Nrf2 After Fumarate Treatment for Multiple Sclerosis and Psoriasis
Von Metz et al, erschienen in „Neurol Neuroimmunol Neuroinflamm“ (Vol. 2, Nr. 3, April 2015)

Antibodies to the inward rectifying potassium channel 4.1 in multiple sclerosis: different methodologies–conflicting results?
Von Hemmer B., erschienen in „Multiple Sclerosis Journal“ (Vol. 21, Nr. 5, April 2015)

The impact of isolated lesions on white-matter fiber tracts in multiple sclerosis patients
Von Droby et al, erschienen in „NeuroImage: Clinical“ (Vol. 8, April 2015)

High CCR5 expression in natalizumab-associated progressive multifocal leukoencephalopathy immune reconstitution inflammatory syndrome supports treatment with the CCR5 inhibitor maraviroc
Von Stork et al, erschienen in „Acta Neuropathol.“ (Vol. 129, Nr. 3, März 2015)

Evaluator-blinded trial evaluating nurse-led immunotherapy DEcision Coaching In persons with relapsing-remitting Multiple Sclerosis (DECIMS) and accompanying process evaluation: study protocol for a cluster randomised controlled trial
Von Rahn et al, erschienen in „Trials“ (Vol. 16, Nr. 1, März 2015)

Histopathology and clinical course of MOG-antibody-associated encephalomyelitis
Von Spadaro et al, erschienen in „Ann Clin Transl Neurol.“ (Vol. 2, Nr. 3, März 2015)

Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab
Von Villar et al, erschienen in „Ann Neurol.“ (Vol. 77, Nr. 3, März 2015)

Cross-recognition of a myelin peptide by CD8+ T cells in the CNS is not sufficient to promote neuronal damage
Von Reuter et al, erschienen in „Journal of Neuroscience“ (Vol. 35, Nr. 12, März 2015)

Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria
Von Schippling et al, erschienen in „Mult Scler.“ (Vol. 21, Nr. 2, Februar 2015)

MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4
Von Walsh et al, erschienen in „J Clin Invest.“ (Vol. 125, Nr. 2, Februar 2015)

Fingolimod treatment promotes regulatory phenotype and function of B cells
Von Grützke et al, erschienen in „Ann Clin Transl Neurol.“ (Vol. 2, Nr. 2, Februar 2015)

Natalizumab restores aberrant miRNA expression profile in multiple sclerosis and reveals a critical role for miR-20b
Von Ingwersen et al, erschienen in „Ann Clin Transl Neurol.“ (Vol. 2, Nr. 1, Januar 2015)

Capillary isoelectric focusing immunoassay as a new nanoscale approach for the detection of oligoclonal bands
Von Halbgebauer et al, erschienen in „Electrophoresis“ (Vol. 36, Nr. 2, Januar 2015)

Lack of efficacy of mitoxantrone in primary progressive Multiple Sclerosis irrespective of pharmacogenetic factors: A multi-center, retrospective analysis
Von Grey et al, erschienen in „J Neuroimmunol.“ (Vol. 278, Januar 2015)

The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity
Von Hoffmann et al, erschienen in „J Immunol.“ (Vol. 194, Nr. 2, Januar 2015)

Therapeutic uses of anti-α4-integrin (anti-VLA-4) antibodies in multiple sclerosis
Von Schwab et al, erschienen in „Int Immunol.“ (Vol. 27, Nr. 1, Januar 2015)

The cerebrospinal fluid immunoglobulin transcriptome and proteome in neuromyelitis optica reveals central nervous system-specific B cell populations
Von Kowarik et al, erschienen in „J Neuroinflammation“ (Vol. 12, Nr. 19, Januar 2015)

Severe cognitive impairment associated with intrathecal antibodies to the NR1 subunit of the N-methyl-D-aspartate receptor in a patient with MS
Von Fleischmann et al, erschienen in „JAMA Neurol.“ (Vol. 72, 1, Januar 2015)

Publikationen 2014

Effects of blood transportation on human peripheral mononuclear cell yield, phenotype and function: implications for immune cell biobanking
Von Posevitz-Fejfár et al, erschienen in „PLoS One“ (Vol. 9, Nr. 12, Dezember 2014)

A recoverable state of axon injury persists for hours after spinal cord contusion in vivo
Von Williams et al, erschienen in „Nat Commun.“ (Vol. 5, Nr. 5683, Dezember 2014)

Cerebrospinal fluid JC virus antibody index for diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy
Von Warnke et al, erschienen in „Ann Neurol.“ (Vol. 76, Nr. 6, Dezember 2014)

Initial lymphocyte count and low BMI may affect fingolimod-induced lymphopenia
Von Warnke et al, erschienen in „Neurology“ (Vol. 83, Nr. 23, Dezember 2014)

Pervasive axonal transport deficits in multiple sclerosis models
Von Sorbara et al, erschienen in „Neuron“ (Vol. 84, Nr. 6, Dezember 2014)

Identical lesion morphology in primary progressive and relapsing-remitting MS–an ultrahigh field MRI study
Von Kuchling et al, erschienen in „Mult Scler.“ (Vol. 20, Nr. 14, Dezember 2014)

Review: Mode of action and clinical studies with fumarates in multiple sclerosis
Von Salmen A und Gold R, erschienen in „Exp Neurol.“ (Vol. 262, Part A, Dezember 2014)

Treg cells mediate recovery from EAE by controlling effector T cell proliferation and motility in the CNS
Von Koutrolos et al, erschienen in „Acta Neuropathol Commun.“ (Vol. 2, Dezember 2014)

Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination
Von Mohan et al, erschienen in „Acta Neuropathol Commun.“ (Vol. 2, Dezember 2014)

Intact protein analysis of ubiquitin in cerebrospinal fluid by multiple reaction monitoring reveals differences in Alzheimer’s disease and frontotemporal lobar degeneration
Von Oeckl et al, erschienen in „J Proteome Res.“ (Vol. 13, Nr. 11, November 2014)

Magnetic Resonance Imaging in Multiple Sclerosis – Patients‘ Experiences, Information Interests and Responses to an Education Programme
Von Brand et al, erschienen in „PLoS One“ (Vol. 9, Nr. 11:e113252, November 2014)

Cardiotoxicity of mitoxantrone treatment in a german cohort of 639 multiple sclerosis patients
Von Fleischer et al, erschienen in „J Clin Neurol.“ (Vol. 10, Nr. 4, Oktober 2014)

Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammation
Von Beltrán et al, erschienen in „Brain“ (Vol. 137, Pt 10, Oktober 2014)

Guidelines for uniform reporting of body fluid biomarker studies in neurologic disorders
Von Gnanapavan et al, erschienen in „Neurology“ (Vol. 83, Nr. 13, September 2014)

Review: Microglia: unique and common features with other tissue macrophages
Von Prinz et al, erschienen in „Acta Neuropathol.“ (Vol. 128, Nr. 3, September 2014)

A unified cell biological perspective on axon-myelin injury
Von Simons et al, erschienen in „J Cell Biol.“ (Vol. 206, Nr. 3, August 2014)

The investigation of acute optic neuritis: a review and proposed protocol
Von Petzold et al, erschienen in „Nat Rev Neurol.“ (Vol. 10, Nr. 8, August 2014)

Human CD4+HLA-G+ regulatory T cells are potent suppressors of graft-versus-host disease in vivo
Von Pankratz et al, erschienen in „FASEB J.“ (Vol. 28, Nr. 8, August 2014)

VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells
Von Schneider-Hohendorf et al, erschienen in „J Exp Med.“ (Vol. 211, Nr. 9, August 2014)

Review: Immunophenotyping of Cerebrospinal Fluid Cells in Multiple Sclerosis: In Search of Biomarkers
Von Alvermann et al, erschienen in „JAMA Neurol.“ (Vol. 71, Nr. 7, Juli 2014)

Aquaporin-4 antibody testing: direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate
Von Jarius et al, erschienen in „J Neuroinflammation“ (Vol. 11, Nr. 129, Juli 2014)

Interferon β-1a reduces increased interleukin-16 levels in multiple sclerosis patients
Von Nischwitz et al, erschienen in „Acta Neurol Scand“ (Vol. 130, Nr. 1, Juli 2014)

Differential loss of KIR4.1 immunoreactivity in multiple sclerosis lesions
Von Schirmer et al, erschienen in „Ann Neurol.“ (Vol. 75, Nr. 6, Juni 2014)

Nurse-led immunotherapy DEcision Coaching In Multiple Sclerosis (DECIMS) – design and feasibility study for a cluster-randomised controlled trial
Von Rahn et al, erschienen in „MSJ“ (Vol. 20, Nr. 7, Juni 2014)

Management of disease modifying treatments in neurological autoimmune diseases of the central nervous system
Von Salmen et al, erschienen in „Clin Exp Immunol“ (Vol. 176, Nr. 2, Mai 2014)

Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo
Von Breckwoldt et al, erschienen in „Nat Med.“ (Vol. 20, Nr. 5, Mai 2014)

Neuromyelitis optica: clinical features, immunopathogenesis and treatment
Von Jarius et al, erschienen in „Clin Exp Immunol.“ (Vol. 176, Nr. 2, Mai 2014)

Pathologic heterogeneity persists in early active multiple sclerosis lesions
Von Metz et al, erschienen in „Ann Neurol“ (Vol. 75, Nr. 5, Mai 2014)

Chemokine-mediated redirection of T cells constitutes a critical mechanism of glucocorticoid therapy in autoimmune CNS responses
Von Schweingruber et al, erschienen in „Acta Neuropathol“ (Vol. 127, Nr. 5, Mai 2014)

Review: Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
Von Prinz M und Priller J, erschienen in „J Nat Rev Neurosci.“ (Vol. 15, Nr. 5, Mai 2014)

NF-κB signaling regulates myelination in the CNS
Von Blank T und Prinz M, erschienen in „Front Mol Neurosci.“ (Vol. 7, Nr. 47, Mai 2014)

B cells in multiple sclerosis: good or bad guys?: An article for 28 May 2014 – World MS Day 2014
Von Hoffmann F und Meinl E, erschienen in „Eur J Immunol.“ (Vol. 44, Nr. 5, Mai 2014)

Review: B cells in MS and NMO: pathogenesis and therapy
Von Krumbholz M und Meinl E, erschienen in „Semin Immunopathol.“ (Vol. 36, Nr. 3, Mai 2014)

Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity
Von Breuer et al, erschienen in „Ann Neurol.“ (Vol. 75, Nr. 5, Mai 2014)

JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants
Von Sundqvist et al, erschienen in „PLoS Pathog.“ (Vol. 10, Nr. 4, April 2014)

Efficacy and side effects of natalizumab therapy in patients with multiple sclerosis
Von Hoepner et al, erschienen in „J Cent Nerv Syst Dis.“ (Vol. 6, April 2014)

Cerebrospinal fluid immunoglobulin kappa light chain in clinically isolated syndrome and multiple sclerosis
Von Senel et al, erschienen in „PLoS One“ (Vol. 9, Nr. 4: e88680, April 2014)

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases
Von Shen et al, erschienen in „Nature“ (Vol. 507, Nr. 7492, März 2014)

Comment: New evidence for teriflunomide in multiple sclerosis
Von Kieseier BC und Wiendl H, erschienen in „Lancet Neurol.“ (Vol. 13, Nr. 3, März 2014)

Review: To look for a needle in a haystack: the search for autoantibodies in multiple sclerosis
Von Schirmer et al, erschienen in „Mult Scler.“ (Vol. 20, Nr. 3, März 2014)

Increased cortical curvature reflects white matter atrophy in individual patients with early multiple sclerosis
Von Deppe et al, erschienen in „Neuroimage Clin.“ (Vol. 6, Nr. 4, März 2014)

The neuroinflammation biobank in the Department of Neurology, University Hospital Muenster, Germany
Von Posevitz-Fejfár A und Wiendl H, erschienen in „Biopreserv Biobank“ (Vol. 12, Nr. 1, Februar 2014)

Selective accumulation of pro-inflammatory T cells in the intestine contributes to the resistance to autoimmune demyelinating disease
Von Berer et al, erschienen in „PLoS One“ (Vol. 9, Nr. 2:e87876, Februar 2014)

The fraction of varicella zoster virus-specific antibodies among all intrathecally-produced antibodies discriminates between patients with varicella zoster virus reactivation and multiple sclerosis
Von Otto et al, erschienen in „Fluids Barriers CNS“ (Vol. 11, Nr. 1:3, Februar 2014)

Potassium channel KIR4.1-specific antibodies in children with acquired demyelinating CNS disease
Von Kraus et al, erschienen in „Neurology“ (Vol. 82, Nr. 6, Februar 2014)

Review: Biomarkers of treatment response in multiple sclerosis
Von Buck D und Hemmer B, erschienen in „Expert Rev Neurother.“ (Vol. 14, Nr. 2, Februar 2014)

Immune cell subtyping in the cerebrospinal fluid of patients with neurological diseases
Von Kowarik et al, erschienen in „J Neurol.“ (Vol. 261, Nr. 1, Januar 2014)

Chronic cerebrospinal venous insufficiency in multiple sclerosis: the final curtain
Von Paul F und Wattjes MP, erschienen in „Lancet“ (Vol. 383, Nr. 9912, Januar 2014)

Onset of secondary progressive phase and long-term evolution of multiple sclerosis
Von Scalfari et al, erschienen in „J Neurol Neurosurg Psychiatry“ (Vol. 85, Nr. 1, Januar 2014)

Publikationen 2013

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Von International Multiple Sclerosis Genetics Consortium, erschienen in „Nat Genet.“ (Vol. 45, Nr. 11, November 2013)

Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis
Von Teunissen et al, erschienen in „Mult Scler.“ (Vol. 19, Nr. 13, November 2013)

Natalizumab affects the T-cell receptor repertoire in patients with multiple sclerosis
Von Warnke et al, erschienen in „Neurology“ (Vol. 81, Nr. 16, Oktober 2013)

Natalizumab treatment decreases serum IgM and IgG levels in multiple sclerosis patients
Von Selter et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 19, Nr. 11, Oktober 2013)

Hunting for autoantibodies in multiple sclerosis
Von Hemmer B und Srivastava R, erschienen in „Neurology“ (Vol. 81, Nr. 11, September 2013)

L-Selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients
Von Schwab et al, erschienen in „Neurology“ (Vol. 81, Nr. 10, September 2013)

An assay to quantify species-specific anti-JC virus antibody levels in MS patients
Von Warnke et al, erschienen in „Mult Scler J“ (Vol. 19, Nr. 9, August 2013)

T-cell homeostasis in pediatric multiple sclerosis: old cells in young patients
Von Balint et al, erschienen in „Neurology“ (Vol. 81, Nr. 9, August 2013)

A web-based tool for personalized prediction of long-term disease course in patients with multiple sclerosis
Von Galea et al, erschienen in „European Journal of Neurology“ (Vol. 20, Nr. 7, Juli 2013)

A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity
Von Lodygin et al, erschienen in „Nature Medicine“ (Vol. 19, Nr. 6, Juni 2013)

Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls
Von International Multiple Sclerosis Genetics Consortium, erschienen in „Am J Hum Genet“ (Vol. 92, Nr. 6, Juni 2013)

Neurons as targets for T cells in the nervous systems
Von Liblau et al, erschienen in „Trends in Neurosciences“ (Vol. 36, Nr. 6, Juni 2013)

MANBA, CXR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis
Von International Multiple Sclerosis Genetics Consortium, erschienen in „Brain“ (Vol. 136, Nr. 6, Juni 2013)

Fine-tuning of Regulatory T-Cell Function: the Role of Calcium Signals and Naïve Treg for Treg Deficiency in Multiple Sclerosis?
Von Schwarz et al, erschienen in „J Immunol“ (Vol. 190, Nr. 10, Mai 2013)

Mitoxantrone-related acute leukemia in MS: an open or closed book?
Von Chan A und Lo-Coco F, erschienen in „Neurology“ (Vol. 80, Nr. 16, April 2013)

Cellular, subcellular and functional in vivo labeling of the spinal cord using vital dyes
Von Romanelli et al, erschienen in „Nat Protoc.“ (Vol 8, Nr. 3, März 2013)

Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk
Von Lill et al, erschienen in „J Med Genet.“ (Vol. 50, Nr. 3, März 2013)

Genetic Variants in the Immunoglobulin Heavy Chain Locus are Associated with the Gamma Globulin Index in Multiple Sclerosis
Von Buck et al, erschienen in „Annals of Neurology“ (Vol. 73, Nr. 1, Januar 2013)

Publikationen 2012

Low vitamin D and elevated immunoreactivity against Epstein-Barr virus before first clinical manifestation of multiple sclerosis
Von Décard et al, erschienen in „J Neurol Neurosurg Psychiatry“ (Vol. 83, Nr. 12, Dezember 2012)

Neurofascin as a target for autoantibodies in peripheral neuropathies
Von Ng et al, erschienen in „Neurology“ (Vol. 79, Nr. 23, Dezember 2012)

B cells and antibodies in multiple sclerosis pathogenesis and therapy
Von Krumbholz et al, erschienen in „Nat Rev Neurol“ (Vol. 8, Nr. 11, November 2012)

Therapeutic monitoring of immunotherapies in autoimmune diseases
Von von Ahsen N und Chan A, erschienen in „Current pharmaceutical design“ (Vol. 18, Nr. 29, Oktober 2012)

Prospects of transcript profiling for mRNAs and MicroRNAs using formalin-fixed and paraffin-embedded dissected autoptic multiple sclerosis lesions
Von Eisele et al, erschienen in „Brain Pathol.“ (Vol. 22, Nr. 5, September 2012)

Closing the case of APOE in multiple sclerosis: no association with disease risk in over 29 000 subjects
Von Lill et al, erschienen in „J Med Genet.“ (Vol. 49, Nr. 9, September 2012)

T cells become licensed in the lung to enter the central nervous system
Von Odoardi et al, erschienen in „Nature“ (Vol. 488, Nr. 7413, August 2012)

Biocompatibility of a genetically encoded calcium indicator in a transgenic mouse model
Von Direnberger et al, erschienen in „Nature Communications“ (Vol. 3, Nr. 1031, August 2012)

Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor(+) Regulatory T Cells
Von Yogev et al, erschienen in „Immunity“ (Vol. 37, Nr. 2, August 2012)

The ambivalent role of apoptosis in experimental autoimmune
Von Reichardt HM und Lühder F, erschienen in „Curr Pharm Des“ (Vol. 18, Nr. 29, Juli 2012)

The Potassium Channel KIR4.1 as an Immune Target in Multiple Sclerosis
Von Srivastava et al, erschienen in „N Eng J Med“ (Vol. 367, Nr. 2, Juli 2012)

Anti-JCV antibody prevalence in a German MS cohort
Von Warnke et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 18, Nr. 7, Juli 2012)

Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis
Von Elliott et al, erschienen in „BRAIN“ (Vol. 135, Nr. 6, Juni 2012)

Identifying autoantigens in demyelinating diseases: valuable clues to diagnosis and treatment?
Von Derfuss T und Meinl E, erschienen in „Curr Opin Neurol.“ (Vol. 25, Nr. 3, Juni 2012)

Single nucleotide polymorphisms in HLA- and non-HLA genes associated with the development of antibodies to interferon-ß therapy in multiple sclerosis patients
Von Weber et al, erschienen in “ The Pharmacogenomics Journal“ (Vol. 12, Nr. 3, Juni 2012)

Commensal gut flora and brain autoimmunity: a love or hate affair?
Von Berer et al, erschienen in „Acta Neuropathologica“ (Vol. 123, Nr. 5, Mai 2012)

CXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammation
Von Kowarik et al, erschienen in „J Neuroinflammation“ (Vol. 9, Nr. 93, Mai 2012)

Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more
Von Mayer et al, erschienen in „Therapeutic Advances in Neurological Disorders“ (Vol. 5, Nr. 3, Mai 2012)

Anti-JC virus antibodies in a large German natalizumab-treated multiple sclerosis cohort
Von Trampe et al, erschienen in „Neurology“ (Vol. 78, Nr. 22, Mai 2012)

Immunological and clinical consequences of treating a patient with natalizumab
Von Schwab et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 18, Nr. 3, März 2012)

Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration
Von Colombo et al, erschienen in „The Journal of Experimental Medicine“ (Vol. 209, Nr. 3, März 2012)

Pathology of immune reconstitution inflammatory syndrome in multiple sclerosis with natalizumab-associated progressive multifocal leukoencephalopathy
Von Metz et al, erschienen in „Acta Neuropathologica“ (Vol. 123, Nr. 2, Februar 2012)

Primary oligodendrocyte death does not elicit anti-CNS immunity
Von Locatelli et al, Online-Veröffentlichung (Epub ahead of print) „Nature Neuroscience“ (26. Februar 2012)

An automated tool for detection of FLAIR-hyperintense white-matter lesions in multiple sclerosis
Von Schmidt et al, erschienen in „Neuroimage“ (Vol. 59, Nr. 4, Februar 2012)

Fatal PML associated with efalizumab therapy. Insights into integrin αLβ2 in JC virus control
Von Schwab et al, erschienen in „Neurology“ (Vol. 78, Nr. 7, Februar 2012)

Independent replication of STAT3 association with multiple sclerosis risk in a large German case-control sample
Von Lill et al, erschienen in „Neurogenetics“ (Vol. 13, Nr. 1, Februar 2012)

Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination
Von Lee et al, erschienen in „Acta Neuropathologica“ (Vol. 123, Nr. 2, Februar 2012)

Incidence of therapy-related acute leukaemia in mitoxantrone-treated multiple sclerosis patients in Germany
Von Stroet et al, erschienen in „Therapeutic Advances in Neurological Disorders“ (Vol. 5, Nr. 2, Januar 2012)

Publikationen 2011

B cells undergo unique compartmentalized redistribution in multiple sclerosis
Von Haas et al, erschienen in „Journal of Autoimmunity“ (Vol. 37, Nr. 4, Dezember 2011)

Ion channels in autoimmune neurodegeneration
Von Ehling et al, erschienen in „FEBS letters“ (Vol. 585, Nr. 23, Dezember 2011)

Autoimmune disease in the brain – how to spot the culprits and how to keep them in check
Von Flügel et al, erschienen in „Journal of the Neurological Sciences“ (Vol. 311, S 1, Dezember 2011)

Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS
Von Dann et al, erschienen in „Nature Neuroscience  “ (Vol. 15, Nr. 1, Dezember 2011)

Natalizumab and impedance of the homing of CD34+ hematopoietic progenitors
Von Saure et al, erschienen in „Archives of Neurology“ (Vol. 68, Nr. 11, November 2011)

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
Von Berer et al, erschienen in „Nature“ (Vol. 479, Nr. 7374, November 2011)

Pharmacogenomics in Neurology: Current State and Future Steps
Von Chan et al, erschienen in „Annals of Neurology“ (Vol. 70, Nr. 5, November 2011)

Diagnostik der Multiplen Sklerose – 2010 Revision der McDonald-Kriterien
Von Klotz et al, erschienen in „Der Nervenarzt“ (Vol. 82, Nr. 10, Oktober 2011)

Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders
Von Lehmann-Horn et al, erschienen in „Journal of Neuroinflammation“ (Vol. 8, Nr. 146, Oktober 2011)

Treatment of multiple sclerosis: current concepts and future perspectives
Von Buck D. und Hemmer B., erschienen in „Journal of Neurology“ (Vol. 258, Nr. 10, Oktober 2011)

Risikostratifizierung einer progressiven multifokalen Leukenzephalopathie unter Natalizumab
Von Warnke et al, erschienen in „Der Nervenarzt“ (Vol. 82, Nr. 10, Oktober 2011)

Liposomal encapsulation of glucocorticoids alters their mode of action in the treatment of experimental autoimmune encephalomyelitis
Von Schweingruber et al, erschienen in „Journal of Immunology“ (Vol. 187, Nr. 8, Oktober 2011)

ATP-Binding Cassette Transporters in Inflammatory Brain Disease
Von Chan et al, erschienen in „Current Pharmaceutical Design“ (Vol. 17, Nr. 26, September 2011)

Age and disability accumulation in multiple sclerosis
Von Scalfari et al, erschienen in „Neurology“ (Vol. 77, Nr. 13, September 2011)

CXCL12 expression within the CNS contributes to the resistance against experimental autoimmune encephalomyelitis in Albino Oxford rats
Von Miljković et al, erschienen in „Immunobiology“ (Vol. 216, Nr. 9, September 2011)

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Von: The International Multiple Sclerosis Genetics Consortium (IMSGC) and the Wellcome Trust Case Control Consortium 2 (WTCCC2), erschienen in „Nature“ (Vol. 476, Nr. 7359, August 2011)

Association between Walking Speed and Age in Healthy, Free-Living Individuals Using Mobile Accelerometry-A Cross-Sectional Study
Von Schimpl et al, erschienen auf „PLoS One“ (Vol. 6, Nr. 8, August 2011)

Evaluation of soluble HLA-G as a biomarker for multiple sclerosis
Von Waschbisch et al, erschienen in „Neurology“ (Vol. 77, Nr. 6, August 2011)

Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis
Von Pröbstel et al, erschienen in „Neurology“ (Vol. 77, Nr. 6, August 2011)

Development and validation of a new method to measure gait d speed using mobile accelerometry
Von Schimpl et al, erschienen auf „PLoS One“ (Vol. 6, Nr. 8, August 2011)

Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channels
Von Bobak et al, erschienen in „Biochimica et Biophysica Acta (BBA) – Biomembranes“ (Vol. 1808, Nr. 8, August 2011)

Humoral autoimmunity in multiple sclerosis
Von Meinl et al, erschienen in „Journal of the Neurological Sciences“ (Vol. 306, Nr. 1-2, Juli 2011)

MRI Pattern Recognition in Multiple Sclerosis Normal-Appearing Brain Areas
Von Weygandt et al, erschienen auf „PLoS One“ (Vol. 6, Nr. 6, Juni 2011)

More CLEC16A gene variants associated with multiple sclerosis
Von Nischwitz et al, erschienen in „Acta Neurologica Scandinavica“ (Vol. 123, Nr. 6, Juni 2011)

Risks and benefits of multiple sclerosis therapies: need for continual assessment?
Von Kieseier et al, erschienen in „Current Opinion in Neurology“ (Vol. 24, Nr. 3, Juni 2011)

Progressive multifokale Leukenzephalopathie unter Natalizumab
Erste Möglichkeiten einer Risikostratifizierung?

Von Warnke et al, erschienen in „Der Nervenarzt“ (Vol. 82, Nr. 4, April 2011)

Long-term follow-up of patients with Neuromyelitis optica after repeated therapy with rituximab
Von Pellkofer et al, erschienen in „Neurology“ (Vol. 76, Nr. 15, April 2011)

Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin
Von Obermeier et al, erschienen in „Journal of Neuroimmunology“ (Vol. 233, Nr. 1-2, April 2011)

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis
Von Nikic et al, erschienen in „Nature Medicine“ (Vol. 17, Nr. 4, April 2011)

Functional energetics of CD4+-cellular immunity in monoclonal antibody-associated progressive multifocal leukoencephalopathy in autoimmune disorders
Von Haghikia et al, erschienen in „PLoS One“ (Vol. 6, Nr. 4, April 2011)

EPIBLASTER-Fast exhaustive two-locus epistasis detection strategy using graphical processing units
Von Kam-Thong et al, erschienen in „European Journal of Human Genetics“ (Vol. 19, Nr. 4, April 2011)

Influence of the HLA-DRB1 Genotype on antibody development to Interferon Beta in Multiple Sclerosis
Von Buck et al, erschienen in „Archives of Neurology“ (Vol. 68, Nr. 4, April 2011)

I B kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF- B in the CNS
Von Raasch et al, erschienen in „BRAIN“ (Vol. 134, Nr. 4, April 2011)

Differential effects of fingolimod (FTY720) on immune cells in the CSF and blood of MS patients
Von Kowarik et al, erschienen in „Neurology“ (Vol. 76, Nr. 14, April 2011)

Intracerebral Human Regulatory T Cells: analysis of CD4+CD25+FOXP3+ T Cells in Brain Lesions and Cerebrospinal Fluid of Multiple Sclerosis Patients
Von Fritzsching et al, erschienen in „PLoS One“ (Vol. 6, Nr. 3, März 2011)

The interleukin-7 receptor a chain contributes to altered homeostasis of regulatory T cells in multiple sclerosis
Von Haas et al, erschienen in „European Journal of Immunology“ (Vol. 41, Nr. 3, März 2011)

Is it possible to measure mobility deficits of patients suffering from multiple sclerosis?
Von Schlesinger et al, erschienen in „Klinische Neurophysiologie“ (Vol. 42, Nr. 1, März 2011)

Therapy for Multiple Sclerosis with Monoclonal Antibodies: Updated Recommendations for the Use of Natalizumab in the Framework of an Expert’s Meeting
Von Hartung et al, erschienen in „Aktuelle Neurologie“ (Vol. 38, Nr. 1, Februar 2011)

Expression of K2P5.1 potassium channels on CD4+ T lymphocytes correlates with disease activity in rheumatoid arthritis patients
Von Bittner et al, erschienen in „Arthritis Research & Therapy“ (Vol. 13, Nr. 1, Februar 2011)

Janus head: the dual role of HLA-G in CNS immunity
Von Huang et al, erschienen in „Cellular and Molecular Life Sciences“ (Vol. 68, Nr. 3, Februar 2011)

Microglia in the CNS: Immigrants from another world
Von M. Prinz und A. Mildner, erschienen in „GLIA“ (Vol. 59, Nr. 2, Februar 2011)

CD34+ progenitor cells mobilized by natalizumab are not a relevant reservoir for JC virus
Von Warnke et al, erschienen in „Multiple Sclerosis“ (Vol. 17, Nr. 2, Februar 2011)

Assessment of JC virus DNA in blood and urine from natalizumab-treated patients
Von Warnke et al, erschienen in „Annals of Neurology“ (Vol. 69, Nr. 1, Januar 2011)

The emerging role of miRNAs in multiple sclerosis
Von Junker et al, erschienen in „Nature Reviews Neurology“ (Vol. 7, Nr. 1, Januar 2011)

Functional characterization of aquaporin-4 specific T cells: towards a model for neuromyelitis optica
Von Kalluri et al, erschienen in „PLoS One“ (Vol. 6, Nr. 1, Januar 2011)

Publikationen 2010

Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in multiple sclerosis patients
Von Schneider-Hohendorf et al, erschienen in „European Journal of Immunology“ (Vol. 40, Nr. 12, Dezember 2010)

A Data Protection Scheme for Medical Research Networks: Review after Five Years of Operation
Von Helbing et al, erschienen in „Methods Inf Med“ (Vol. 49, Nr. 6, Dezember 2010)

Glatiramer Acetate attenuates pro-inflammatory T Cell responses but does not directly protect neurons from inflammatory cell death
Von Herrmann et al, erschienen in „American Journal of Pathology“ (Vol. 177, Nr. 6, Dezember 2010)

Genetic proof for the transient nature of the Th17 phenotype
Von Kurschus et al, erschienen in „European Journal of Immunology“ (Vol. 40, Nr. 12, Dezember 2010)

Temporal Pattern of ICAM-I Mediated Regulatory T Cell Recruitment to Sites of Inflammation in Adoptive Transfer Model of Multiple Sclerosis
Von Doerck et al, erschienen in „Plos one“ (Vol. 5, Nr. 11, November 2010)

ESPED 2009 – Bericht des Beirats
Von Berner et al, erschienen in „Monatsschrift Kinderheilkunde“ (Vol. 158, Nr. 11, November 2010)

B Cells participate in thymic negative selection of murine auto-reactive CD4+ T Cells
Von F. Frommer und A. Waisman, erschienen in „Plos one“ (Vol. 5, Nr. 10, Oktober 2010)

Serum antibodies to conformational and linear epitopes of myelin oligodendrocyte glycoprotein are not elevated in the preclinical phase of multiple sclerosis
Von Chan et al, erschienen in „Multiple Sclerosis Journal“ (Vol. 16, Nr. 10, Oktober 2010)

Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis
Von Nischwitz et al, erschienen in „Journal of Neuroimmunology“ (Vol. 227, Nr. 1-2, Oktober 2010)

Quantification and Functional Characterization of Antibodies to Native Aquaporin 4 in Neuromyelitis Optica
Von Kalluri et al, erschienen in „Archives of Neurology“ (Vol. 67, Nr. 10, Oktober 2010)

Extracellular matrix in multiple sclerosis lesions: fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cells
Von Mohan et al, erschienen in „Brain pathology“ (Vol. 20, Nr. 5, September 2010)

T cell vaccination induces the elimination of EAE effector T cells: analysis using GFP-transduced, encephalitogenic T cells
Von Volovitz et al, erschienen in „Journal of Autoimmunity“ (Vol. 35, Nr. 2, September 2010)

Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis
Von Linker et al, erschienen in “Brain” (Vol. 133, Nr. 8, August 2010)

A Practical guide to pediatric multiple sclerosis
Von P. Huppke und J. Gärtner, erschienen in „Neuropediatrics“ (Vol. 41, Nr. 4, August 2010)

Reduced cortisol levels in cerebrospinal fluid and differential distribution of 11beta-hydroxysteroid dehydrogenases in multiple sclerosis: implications for lesion pathogenesis
Von Heidbrink et al, erschienen in „Brain, Behavior, and Immunity“ (Vol. 24, Nr. 6, August 2010)

FOXP3+ T regulatory cells in idiopathic inflammatory myopathies
Von Waschbisch et al, erschienen in „Journal of Neuroimmunology“ (Vol. 225, Nr. 1-2, August 2010)

Upregulation of K2P5.1 Potassium Channels in Multiple Sclerosis
Von Bittner et al, erschienen in “Annals of Neurology” (Vol. 68, Nr. 1, Juli 2010)

Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system
Von Cordiglieri et al, erschienen in „Brain“ (Vol. 133, Nr. 7, Juli 2010)

Antibody responses to EBV and native MOG in pediatric inflammatory demyelinating CNS diseases
Von Selter et al, erschienen in “Neurology” (Vol. 74, Nr. 21, Mai 2010)

An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in Multiple Sclerosis
Von Schwab et al, erschienen in “Journal of Immunology” (Vol. 184, Nr. 9, Mai 2010)

Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis
Von Kleiter et al, erschienen in „Brain“ (Vol. 133, Nr. 4, April 2010)

The antibody response to oligodendrocyte specific protein in multiple sclerosis
Von Aslam et al, erschienen in “Journal of Neuroimmunology” (Vol. 221, April 2010)

MS-Datenbank erleichtert Forschung
Von Daumer et al, erschienen in “Ärztliche Praxis Neurologie & Psychiatrie“ (Nr. 1, Januar 2010)

Reviews:

Knocking at the brain’s door: intravital two-photon imaging of autoreactive T cell interactions with CNS structures
Von N. Kawakami und A. Flügel, erschienen in „Seminars in Immunopathology“ (Vol. 32, Nr. 3, September 2010)

Beneficial brain autoimmunity?
Von H. Wekerle und R. Hohlfeld, erschienen in “Brain” (Vol. 133, Nr. 8, August 2010)

Axo-glial antigens as targets in multiple sclerosis: implications for axonal and grey matter injury
Von Derfuss et al, erschienen in „Journal of Molecular Medicine“ (Vol. 88, Nr. 8, August 2010)

Neuroprotection, regeneration and immunomodulation: broadening the therapeutic repertoire in multiple sclerosis
Von Aktas et al, erschienen in “Trends in Neuroscience” (Vol. 33, Nr. 3, März 2010)

Publikationen 2009

Antibodies to Native Myelin Oligodendrocyte Glycoprotein in Children with Inflammatory Demyelinating Central Nervous System Disease
Von Brilot et al, erschienen in “Annals of Neurology” (Vol. 66, Nr. 6, Dezember 2009)

Glatiramer acetate improves regulatory T-cell function by expansion of naïve CD4+CD25+FOXP3+CD31+ T-cells in patients with multiple sclerosis
Von Haas et al, erschienen in “Journal of Neuroimmunology” (Vol. 216, Dezember 2009)

Prognosis of the individual course of disease: the elements of time, hetereogeneity and precision
Von Daumer et al, erschienen in “Journal of Neurological Sciences” (Vol. 287, November 2009)

Intrathecal Pathogenic Anti-Aquaporin-4 Antibodies in Early Neuromyelitis Optica
Von Bennett et al, erschienen in “Annals of Neurology” (Vol. 66, Nr. 5, November 2009)

A type I interferon signature in monocytes is associated with poor response to interferon-b in multiple sclerosis
Von Comabella et al, erschienen in “Brain” (Vol. 132, Nr. 12, September 2009)

Specific central nervous system recruitment of HLA-G regulatory T Cells in multiple sclerosis
Von Huang et al, erschienen in “Annals of Neurology” (Vol. 66, Nr. 2, August 2009)

T cell suppression by naturally occurring HLA-G-expressing regulatory CD4 T cells is IL-10-dependent and reversible
Von Huang et al, erschienen in “Journal of Leukocyte Biology” (Vol. 86, August 2009)

ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis
Von Cotte et al, erschienen in “Brain” (Vol. 132, Nr. 9, Juli 2009)

The level of B7 homologue 1 expression on brain DC is decisive for CD8 Treg cell recruitment into the CNS during EAE
Von Zozulya et al, erschienen in “European Journal of Immunology” (Vol. 39, Nr. 6, Juni 2009)

Accelerated course of experimental autoimmune encephalomyelitis in PD-1-deficient central nervous system myelin mutants
Von Kroner et al, erschienen in “The American Journal of Pathology” (Vol. 174, Nr. 6, Juni 2009)

Intracerebral dendritic cells critically modulate encephalitogenic versus regulatory immunerResponses in the CNS
Von Zozulya et al, erschienen in “The Journal of Neuroscience” (Vol. 29, Nr. 1, Januar 2009)